Adrenocorticotropic Activity of Lyophilized Anterior Pituitary Preparation
نویسندگان
چکیده
منابع مشابه
Pituitary adrenocorticotropic activity in altered thyroid function.
Alteration in thyroid state influenced the rate of metabolism of adrenocortical hormone by rats liver tissue in vitro, with proportional change in adrenal weight(Yates, 1958). These experiments suggest that the thyroid function would determine the rate of ACTH secretion in unstressed animals. The present study was undertaken to explore the possibility of difference in pituitary-adrenocortical s...
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The molecular weight of the adrenocorticotropic hormone (ACTH) activity in extracts of the separated anterior and intermediate-posterior lobes of the mouse pituitary was determined by gel filtration in guanidine-HCl. Following dilution or removal of the guanidine-HCl, ACTH activity was quantitated by both radioimmunoassay and bioassay. Extracts of the intermediate-posterior lobe contain approxi...
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The isolation and identification of the anterior pituitary growth hormone as a pure protein were first achieved by Li, Evans, and Simpson (1, 2) in 194445. Their method is a beautiful example of the classical procedures of protein fractionation by the controlled use of salt and of hydrogen ion concentrations. It owes its distinction to the proof that the growth-promoting activity of anterior pi...
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To clarify the physiological role of placental corticotropin-releasing hormone (CRH), we measured plasma CRH, ACTH, and cortisol throughout pregnancy. Cerebrospinal fluid (CSF) CRH levels and ACTH responsiveness to synthetic CRH were also quantified in pregnant and nonpregnant women. Maternal plasma CRH levels, which increased progressively during pregnancy, correlated well with both ACTH and c...
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The pituitary gland, also known as hypophysis, is a small pea-sized gland about 1 cm in diameter and 0.5 to 1 gram in weight. The pituitary gland resides in a small bony cavity situated at the base of the brain, known as sella turcica, and a pituitary stalk (infundibulum) maintains a connection between the pituitary gland and hypothalamus. The secretion of hormones by the pituitary gland is und...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1953
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.73.6_661